
For Lease
Professional Office Space Available
2205 Oregon Pike Lancaster, PA 17601
Lancaster County
Property Information
Total Building Size: 4,532 SF
Available Space: 980 SF
Lease Rate: $1,025/month/Gross
Lease Terms: Negotiable
Zoning: B-1 Commercial, Office, Retail
Date Available: March 1, 2026
Property Highlights
980 +/- SF of professional office space is available on the second floor in the William Penn Commons Professional & Medical Center.
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Brokers
Marisa Benjamin
Property Description
William Penn Commons is a professional office and medical center positioned along the highly traveled Oregon Pike/Route 272 corridor in Manheim Township, an area that continues to experience steady growth in professional & medical services. The corridor has seen increased demand for office space driven by population growth, expanding healthcare providers, and professional services seeking convenient access to Lancaster and surrounding communities.
The available 980± SF suite is located on the second floor and provides ample on-site parking. The interior is efficiently designed with an open reception/work area, two (2) private offices, a kitchenette, and a large rear office or conference room.
The property benefits from strong surrounding tenancy, including established and growing medical and professional practices such as: Randali Centre for Aesthetic Medicine, Sallavanti & Cotter Family Medicine, Keystone Endodontics, Katherine Ni, Periodontics, and Tri-Starr Staffing. This mix of tenants creates an environment that attracts both clients and professionals.
With close proximity to numerous retail and service amenities, as well as quick access to downtown Lancaster, William Penn Commons offers an ideal location for professionals seeking visibility, accessibility, and long-term stability in a growing market.
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